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IVIS Spectrum

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MANUFACTURER Caliper Life Sciences
MODEL Spectrum
ACRONYM IVIS

College of Medicine and Dentistry

AVAILABILITY 10am - 4pm
TRAINING Training is required to use this item and we can arrange this if needed.
PRIMARY CONTACT biomedicalservices@bham.ac.uk
ORGANISATION University of Birmingham

Description

The IVIS Spectrum is the most versatile and advanced in vivo imaging system available on the market today. An optimized set of high efficiency filters and spectral un-mixing algorithms lets you take full advantage of bioluminescent and fluorescent reporters across the blue to near infrared wavelength region. It also offers single-view 3D tomography for both fluorescent and bioluminescent reporters that can be analyzed in an anatomical context using our Digital Mouse Atlas. For advanced fluorescence imaging, the IVIS Spectrum has the capability to use either trans-illumination (from the bottom) or epi-illumination (from the top) to illuminate in vivo fluorescent sources. 3D diffuse fluorescence tomography can be performed to determine source localization and concentration using the combination of structured light and trans illumination fluorescent images. The instrument is equipped with 10 narrow band excitation filters (30nm bandwidth) and 18 narrow band emission filters (20nm bandwidth) that assist in significantly reducing autofluorescence by the spectral scanning of filters and the use of spectral unmixing algorithms. In addition, the spectral unmixing tools allow the researcher to separate signals from multiple fluorescent reporters within the same animal.

Last Updated: 24th April, 2013

IVIS Spectrum University of Birmingham

This M5 equipment data is licensed under the UK Open Government Licence.